Assessment of the Safety of Artemisinin Compounds in Pregnancy

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In 2006 WHO/GMP and TDR convened joint informal consultations to review existing data and policies on the use of artemisinin compounds in pregnancy. At the first consultation experts in reproductive and developmental toxicity discussed new published and unpublished data on the toxicity of artemisinins in rodents and primates. In addition, studies using whole embryo culture as well as isolated cells were reviewed. A second consultation reviewed the recent safety and efficacy data on the use of artemisinin compounds in early pregnancy and outlined new approaches needed to obtain more safety information. Sourced from